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What’s the difference? (Asking as a non-native English speaker)
The key opens what is basically a deadbolt, and the only actual latch for the door.
The “knob” isn’t so much a knob, but a stationary/fixed handle for pulling the door.
Door knob can be twisted to open the door. Door handle is static (it doesn’t twist or move) it’s just a convenient place to grab the door.