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The comic is mostly referring to physics crackpots. People outside academia who rejects current established physics in favor of their own pet theories.
Also with medicine
Like how I reject quantum superposition in favor of my pet theory that it’s really only in one state and the superposition is just a convenient way to refer to the chances of each when you can’t observe it because your observation tools will interfere with it?
The term quantum was made up by a physisyst who couldn’t admit that they didn’t understand math. It spiraled from there.