This website contains age-restricted materials including nudity and explicit depictions of sexual activity.
By entering, you affirm that you are at least 18 years of age or the age of majority in the jurisdiction you are accessing the website from and you consent to viewing sexually explicit content.
I would guess the change would be to produce more bufotenin and less stinging, rather than adding bufotenin out of whole cloth.
Still probably more than one change, but theoretically feasible to manually breed a population of hallucinogenic stinging nettles if you’re open to being stung a lot for testing.
Oh, I thought that it was qualitatively already a psychedelic sting. But yeah, quantity is key here xD