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I actually try to talk to folks to the level of their knowledge. I had a debate with some coworkers about vaccines. I explained to them that it’s safe, thousands of studies proved they are, I also mentioned vaccines are produced just like any medicine. And yet people take paracetamol willy nilly without question but somehow treat vaccines differently; even though overusing paracetamol could lead to hearing loss as happened to my dad.
However, I admit that what got me is the mRNA vaccine technology when a colleague said there has been no human trial of it before. The technology has actually been developed for over 40 years but with strong proof of concept. But I find it hard to explain that to laypeople.