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Obviously intent comes into it, where wearing a reductive costume without any awareness (your Halloween costume example) is callous and ignorant of that person. I think some ignorance can be excused if this person couldn’t reasonably be expected to understand all the implications of a costume, even if it’s someone who should be expected to (thinking Trudeau Jr or Prince Harry when younger).
Regardless of the hypothesised (or real) impact to the community of someone wearing clothing arguably offensive to minorities with ancestry in the culture being mocked, those aspects aren’t what this cartoon is about. It’s about idiots who don’t understand nuance and repeat shit they see on social media unthinkingly until you get this absurd situation where someone wearing a hat and wearing it well is screamed at in public for no discernible reason.
Lots of people seeing it will do the same kind of wrong-generalisation in the opposite direction though, and take the valid point the cartoon makes to write off all concerns with cultural appropriation, including the valid ones you just made in your first paragraph.
The world is nuanced, and that’s nearly never conveyed well in our current public communications systems…
I wasn’t responding to the cartoon, but to one comment asking why cultural appropriation is a bad thing.