I have personally seen and always get told in comments etc., that builtin “adblockers” often fail or even deactivate on sites like YouTube etc. And there are always news about YouTube executing another genius strike, forcing everyone to disable their AdBlocker, due to non-loading videos, infinite forced ads etc. Yet - I never had any problems with uBlock + FF. Either it’s not affected in the first place, or fixed faster than Muskler can “Give out his heart”. And it does make sense - a nonprofit, open source extension is gonna be much more flexible than a rigid part of a for-profit browser. Brave/Opera users don’t even really care about actually blocking ads, I believe, they just like the placebo effect believing that anything has changed for the better.
It could also be that uBlock + FF users are more likely to also use NoScript, which does a great deal of blocking ads and adblock detection systems. With some selecting, even extremely ad-infested sites like soap2day.pe work like a charm.

The only times where uBlock has “failed” me: Some random website has a blank space instead of an Ad/Nothing, and every 10-20 videos on Pornhub, there’s a popup.