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some people are sensitive they can get a really bad rash from it.
It’s nuts how different people are. I don’t react to mosquito bites, but my friend gets really itchy red welts from them that linger.
you can get sensitized to allergens and bug bites. im guessing its different if its purified and then injected than maybe. funny thing mosquitoes have complex salival compounds that initially suppresses the immune system, once it wears off the body reacts to the proteins.