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At the end there will always be some way since to the user the text should be similar or the UI should be similar… So there will be always a way… But yeah it can get more complex.
The only exception is the case they implement the web integrity thing at browser level or equivalent.
But then others browsers like Firefox will gain popularity… I am okay whatever they do, I never see any ad or ad-blocker blocker and I doubt I will even see any of those.