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If something hits harder and faster, I’m pretty sure definitionally its more potent.
Potency is a function of its effect relative to the amount used. Like this is more of “yes, AND” type deal, I’m not wrong and you’re right to elaborate that this is due to its increased abillity to permeate BBB
Unless we’re getting into racemics , I’m saying its basically amphetamine + methyl group, lets not get so granular here
Also, meth and amphetamine can be taken such that the doses are equipotent, it would just be less meth and more amphetamine by weight/dosage (all other things like ROA and context being equal)
Re:Serotonin: I believe amphet and meth both affect serotonin dose dependant but I dont think there’s any way to say only meth also implicates serotonergic release or transmission