Could the sweetened drinks we're consuming be making us feel a little more anxious? A 2022 study looking at the effects of the artificial sweetener aspartame on mice suggests that it's a possibility that's worth investigating further.
    • Silverseren@kbin.social
      87·
      1 year ago

      Just in case you missed it, we discussed below that that’s the 15% daily recommended amount for a human. That they gave to the mice. A creature several hundred times smaller.

      So you were right in the first place.

      • smooth_tea@lemmy.world
        4·
        1 year ago

        No, it’s the equivalent dose.

        When a sample of mice were given free access to water dosed with aspartame equivalent to 15 percent of the FDA’s recommended maximum daily amount for humans, they generally displayed more anxious behavior in specially designed mood tests.

      • papertowels@programming.dev
        1·
        1 year ago

        Can you cite your sources? This excerpt from the published article suggests you’re wrong:

        The FDA recommended maximum DIV for aspartame for humans is 50 mg/kg (33). Based on allometric conversion utilizing pharmacokinetic and body surface area parameters (43), the mouse equivalent of the human DIV is 615 mg/kg/d. Therefore, the male mice received a daily aspartame dose equivalent to 14.0%, 7.0%, and 3.5% of the FDA recommended human DIV, and the females received a dose equivalent to 15.5%, 7.7%, and 3.9% of the human DIV.