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You can never disable those aliases, though. The best you can do is write a filter that sends them to trash. With a good email alias system, you can actually disable an alias, so that emails to it just bounce back.
Many services just strip out everything at the + so I instead have a catchall account use email addresses like
sitename@example.com
. For addresses that start getting spam, I add them to a config in rspamd that bounces them. (I self-host my email server)