

For me I noticed minor benefits after 4 days, and it took about 2 weeks for it to more fully kick in.
Personally the other side effects ended up with me going off it. The focus benefits stayed, though the low mood it turned out it was causing took 3 weeks to go away after I stopped.
my male genitals are not working well
This is a common side effect.
It varies in practice. Most people I see using identify, including many trans people, are well-intentioned and think it’s the preferred polite language without thinking too hard on the implications of it.
However there are definitely anti-trans people who will use it pejoratively, which I presume is where that wording originated.