• @[email protected]
    link
    fedilink
    1598 months ago

    Sounds philosophically consistent. What could be more pro-life, pro-business and pro-freedom than being in favour of endless cell growth unchecked by cell apoptosis? Come to think of it, not only does curing cancer sound like a socialist anti-prosperity regulatory agenda, killing off cells that would naturally grow is a little too close to abortion.

  • @[email protected]
    link
    fedilink
    1358 months ago

    Conservatives are generally opposed to any healthcare they personally do not need at the moment. They distrust science, education and medicine. Given a choice, most conservatives would dissolve all scientific research in the U.S.

    Conservatism is a plague of idiocy, sickness and death. This has been true throughout all recorded history.

  • @[email protected]
    link
    fedilink
    106
    edit-2
    8 months ago

    Fun fact! Cuba has a vaccine for lung cancer - yes, it works and has been independently verified. No, you can’t have it because embargo.

    EDIT: vaccine here isn’t actually what I thought. In this case it is a treatment to be used for certain kinds of lung cancer, not a preventative measure as we are used to thinking of Vaccine. Thanks to the comment below for going through it and pushing me to do proper research.

    While my initial take was a glib link to a wikipedia page and not thoroughly researched, I do sill believe that the embargo has directly caused this treatment to come to market in the west as the levels of cooperation are non-existent. It has been used for 7 years in Cuba but is only now entering Stage 3 trials in the US.

    Cuba have also became the first country to have 0 mother-child transmissions of HIV.

    But the US has decided that working with Cuba to prevent hundreds of thousands of deaths each year (in the States alone) is less important than causing “economic dissatisfaction and hardship” to the Cuban people.

    • @[email protected]
      link
      fedilink
      123
      edit-2
      8 months ago

      Slight correction on that vaccine, the FDA doesn’t authorize any drug for sale in the US that hasn’t passed it’s rigorous trials and gone through its approval process. It’s currently being tested and has more trials ongoing right now. FDA will be able to approve it for sale if it passes its trials.

      https://ascopubs.org/doi/10.1200/JCO.2023.41.16_suppl.9135

      Also the word cancer vaccine kind of implies cure to some, but it’s not by any means:

      “MST was 10.83 months for vaccinated vs. 8.86 months for non-vaccinated. In the Phase III trial, the 5-year survival rate was 14.4% for vaccinated subjects vs. 7.9% for controls.”

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346887/

      So it might be a useful tool but just don’t want to get hopes up unnecessarily. People who’s immune system reacted to the vaccine the strongest did best, so current trials are focused on combining it with an immune checkpoint inhibitor drug to increase the immune response even more hopefully (and those drugs are already being used by themselves in cancer). These drugs block “checkpoints” in the immune system that would normally stop it from attacking things like yourself, which we kind of want it to do in cancer.

      Not saying I support an embargo in Cuba, I don’t, just don’t want this comment to be inadvertently read as “Cuba has had the cure to lung cancer this whole time and you’re not allowed to have it!” which isn’t true.

      • @[email protected]
        link
        fedilink
        English
        54
        edit-2
        8 months ago

        Wow this comment really unwinds the one you replied to, so much so that the original seems in bad faith

        Edit op edited, and improved their comment. You don’t need to defend them, they are fine on their own

        • @[email protected]
          link
          fedilink
          118 months ago

          I mean, it’s still true that Cuba has likely made significant advances in the cancer medicine, but it hasn’t passed the standards of the FDA yet. And it’s still true that the embargo between Cuba and the US is upheld to this day by politicians despite the potential good that could come from opening up trade again.

          The first comment to me reads as more just overly enthusiastic, more than explicitly bad faith to me.

        • @[email protected]
          link
          fedilink
          3
          edit-2
          8 months ago

          Definitely wasn’t bad faith and I do stand by it.

          Vaccine does not mean cure. We did not have a Covid cure either. And much like the covid vaccine isn’t 100% effective, neither is this. However, it is proving effective, especially in combination with other drugs and at certain stages of treatment.

          Stage 4 clinical trials were concluded in Cuba in 2017. Stage 2 trials were concluded in the US in 2023. I believe, strongly, that the embargo has increased the amount of time the research has taken - cooperation is impossible during an embargo.

          Even if they lift the embargo tomorrow the drug wouldn’t come on the market, however it is because of the embargo that the use in treatment has taken far, far longer than it would have otherwise.

          Edit: I admit I knew less about the vaccine than I thought I did (edited my comment to reflect what I have learnt)

          • @[email protected]
            link
            fedilink
            English
            4
            edit-2
            8 months ago

            “yes, it works, and has been independently verified” makes it seem like it is 100% ready for us markets but not available. That’s not the case, and it seems you knew that.

            • @[email protected]
              link
              fedilink
              2
              edit-2
              8 months ago

              100% ready for us markets

              How would that be possible during an embargo?

              If a treatment is developed in the EMA, there’s a level of cooperation that means drugs can come to market quickly if proven safe and even somewhat effective (Covid vaccine is an extreme example). This treatment would likely be US ready without the embargo in place.

              it seems you knew that

              My original comment was a glib link to a wikipedia page. I had not done the research and have edited my comment above.

          • @[email protected]
            link
            fedilink
            3
            edit-2
            8 months ago

            I agree it may have presented barriers for coordination the FDA and access to US markets. I haven’t been able to dig deep into the Cuban studies, but just because something is labeled a phase 3 or phase 4 by the investigators doesn’t necessarily mean it was done to the standards necessary for fda approval or in the correct context of current standard of care treatments in the US or who knows how many other issues. If it was fully ready for all markets as is and required no further investigations, and it was only the US FDA causing problems, I would expect it to have already been widely available in many other countries that don’t have embargos with Cuba, like all of Europe. Currently it’s only available in Cuba, Colombia, Bosnia and Herzegovina, Peru, and Paraguay.

            Mostly though I didn’t want someone to accidentally misread this and think it meant cure. I realize you did not say that, but it’s just a common misreading I’ve noticed people make of the term cancer vaccines when they’ve been mentioned in popular media. Didn’t want someone to drag their poor dying relative off to Paraguay thinking they’re getting cured.

            I agree the Cuban embargo is ridiculous, should be stopped, and is hurting both countries with no benefit to anyone (other than keeping a certain segment of voters in Florida happy).

            • @[email protected]
              link
              fedilink
              28 months ago

              like all of Europe

              While Europe does not have an embargo, up until 2016 the EU and Cuba basically had 0 relationship. The EU created “The Common Position” in 1996 which was “to encourage a process of transition to a pluralist democracy” in Cuba which the Cuba government rejected as meddling in their internal affairs.

              Then in the 2000s there was a bigger spat where Cuba even started rejecting EU aid.

              But since 2017 they’ve actually really warmed relations so this is a super good point!

              Thank you for kicking off these research dives with your comments.

          • @[email protected]
            link
            fedilink
            English
            2
            edit-2
            8 months ago

            The incomplete characterization that the drug was READY for us markets.

            It is not fda approved.

            Edit After discussion, the op elected to make the seen edits in their comment. I’d refer you to them.

            • @[email protected]
              link
              fedilink
              28 months ago

              @astreus never made that claim.

              It is currently available in Cuba, Colombia, Bosnia and Herzegovina, Peru and Paraguay.[

              • @[email protected]
                link
                fedilink
                28 months ago

                I agree, I did not make that claim! And I do find it a bit weird that people are using that line of attack. But c’est la vie. I was wrong about what the treatment did, I was wrong about the level of verification it had, however we are singing from the same hymn sheet

                • @[email protected]
                  link
                  fedilink
                  18 months ago

                  For the sake of transparency, I edited before you suggested I did - hence my comment “I had not done the research and have edited my comment above.” 😉

        • @[email protected]
          link
          fedilink
          17
          edit-2
          8 months ago

          It’s also not a vaccine in the sense it’s preventing cancer, it’s for the treatment of cancer that is already there, specifically non small cell lung cancers (though it’s being tested in other cancers that use the signaling mechanism being targeted). Not saying it’s impossible that it could prevent cancer, just that it hasn’t been tested in that way to the best of my knowledge.

          There is some precedence for a vaccine like that though. The HPV vaccine for instance prevents HPV (and therefore hpv related cancers), but is also used as a treatment if an HPV related cancer develops.

      • El Barto
        link
        fedilink
        3
        edit-2
        8 months ago

        its* rigorous trials.

        People whose* immune system.

  • @[email protected]
    link
    fedilink
    English
    928 months ago

    We should keep a record of the nay votes so we can remind them should any of them be diagnosed with cancer.

    • @[email protected]
      link
      fedilink
      278 months ago

      I don’t know how accurate this is

      Biden made a rather cavalier claim that he was going to fund investments in medical science that would lead to a final cure for all forms of cancer within the next decade. And I think we can safely say that’s bullshit.

      However, ramping up blue sky medical research and public sector spending on the adoption of new medical technology would be helpful in treating a host of cancerous maladies and potentially curing or inoculating against others.

      Consider that the US isn’t even on the front line of cancer research anymore. Cuba’s cancer research has outpaced research in the states for over a decade. That, alone, should tell you what kind of progress is possible with a little strategic public investment.

      Whether this is true or not doesn’t change that they openly want to stall government, therefore this could be true.

      Conservatives hate public investment, particularly when it threatens private profits. Liberals do too, abet not as fervently (see: our bipartisan obsession with the health of the domestic automotive, financial, real estate, insurance, and commercial export agricultural industries).

      But this is more an issue of scoring political points. Republicans were happy enough to finance Operation Warp Speed under Trump, in order to fast track the vaccine they thought they’d get to take credit for in 2020. And they loved nothing more than giant state sponsored give-aways to Majority Leader Bill Frist’s family owned Hospital Corporation of America.

      So they’re not strictly against government spending. They simply don’t want another Liberal Democrat like Kennedy taking credit for putting a man on the moon.

      • @[email protected]
        link
        fedilink
        158 months ago

        While I get the point you’re trying to make, it’s just incredibly wrong about cuba. Carry on for the rest.

        Source: I do lots of cancer related research.

          • @[email protected]
            link
            fedilink
            188 months ago

            Not to be pedantic, but an impressive pharmaceutical industry is not the same as leading cancer research. Still impressive. Not the same. Again, I get your point, but no need to exaggerate realities.

            • @[email protected]
              link
              fedilink
              38 months ago

              an impressive pharmaceutical industry is not the same as leading cancer research

              That’s both true and pedantic, but beside the point.

                • @[email protected]
                  link
                  fedilink
                  3
                  edit-2
                  8 months ago

                  Should we be nice to people who are lying?

                  Edit: Downvotes. So, it’s okay ✅ if I lie now. Good to know. You should be very concerned that there are bad actors here, who advocate for lying.

    • TimeSquirrel
      link
      fedilink
      258 months ago

      They aren’t. But if one side could grow a pair instead of pretending that the other side is still willing to debate and act rationally like it’s still the 90s, that would be great.

  • @[email protected]
    link
    fedilink
    53
    edit-2
    8 months ago

    Tbh, a cure for cancer is a little like finding a cure for all respiratory infections. You’re talking about a pathology that encompasses hundreds of distinct diseases. Sure, maybe it is doable, but calling it a moonshot is a little generous; landing on the moon would be several orders of magnitude easier by comparison, imo.

    Just so I’m clear, it’s still shitty that they blocked this.

    • @[email protected]
      link
      fedilink
      39
      edit-2
      8 months ago

      Read the article. It’s pretty clear that cancer is hundreds of different diseases and extremely unlikely to have a single silver bullet, but this description reads more like a coordination project

      the program has made strides in expanding access to cancer detection screenings, especially to veterans, increased support for programs aimed at preventing cancer in the first place and provided funding to groundbreaking cancer cure research

      Its goal is to cut cancer deaths in half by making diagnostics cheaper and more available, funding prevention, and funding research into treatments. No magical silver bullets here

      • @[email protected]
        link
        fedilink
        178 months ago

        When you type out the words “read the article”, it forms a verbal missile of hate aimed right at my heart

        • @[email protected]
          link
          fedilink
          178 months ago

          Ouch. Not intended as that but I do think your concern was answered in the article, and we’re all sometimes guilty of skimming the article or reacting to inflammatory headlines

          • @[email protected]
            link
            fedilink
            118 months ago

            I was being dramatic, no need for alarm. I read several articles a day, typically, but I’m usually pretty selective about it and this one didn’t make the cut, though I still wanted to discuss the topic. So, here we are.

            • @[email protected]
              link
              fedilink
              6
              edit-2
              8 months ago

              I find it interesting that for many serious diseases, the biggest determinant of outcome can be how early you detect it. It’s not something I ever really appreciated before the advent of so many inexpensive tests, and seeing all sorts of stats on just how much difference early detection can make!

              • @[email protected]
                link
                fedilink
                2
                edit-2
                8 months ago

                Yeah, particularly for cancer. Cancer, as I understand it, is a dice game from start to finish. The two commonalities all cancers have are that they’re cells that have immortalized and reproduce out of control. That is, they don’t die when they get signals to die, and they pick up one or more mutations that cause them to undergo cellular division at a higher rate than normal. This is how we still have HeLa cells today. So, the first dice game is getting one cell in your tissue to roll some flavor of those mutations together. From there, the dice start piling up in Cancer’s favor that it can roll more mutations to help it survive when it shouldn’t. The earlier you pick it up, the fewer dice cancer has to play with. Not to mention you’re not also having to fight the battle of trying to kill the cancer while it tries to kill you.

                This is also one of the fronts where it’s thought that mRNA vaccines are going to be huge. In fact, IIRC, the technology was specifically developed with cancer in mind and its use for creating pathogen immunity was a secondary consideration. COVID may have helped catapult that technology years ahead of schedule in terms of development pipeline. IMO, COVID is going to do for medical science what WWII did for machinery, electronics, and atomic science; we’re probably going to start seeing some huge leaps forward in biomedical knowledge and technology coming from theCOVID-centered research initiatives launched all over the world.

                • @[email protected]
                  link
                  fedilink
                  18 months ago

                  Early detection is important for another reason. When trying to kill it you really want to be doing overkill. The less cells it is the less destructive overkill is.

    • @[email protected]
      link
      fedilink
      98 months ago

      Nope, Joe is very, very close to finishing the cure and just needs a little help from Congress to finalize it. But noooo, those dastardly Republicans don’t want him to give us this cure. It’s all their fault.

      Oh, and remember to vote blue no matter who .

      • @[email protected]
        link
        fedilink
        388 months ago

        Look, man, it’s an election year, the hype machine is going to be running full tilt, and every little thing is going to be blown way out of proportion, like that one time Obama killed a fly on national TV or that other time he wore a beige suit. I’m going to vote for Biden, not least of all because the other guy probably will end up putting me and my family on his “official action” list (thank you, SCOTUS). There’s lots more reasons, but Trump openly represents the end of the US government as we’ve known it, and that’s not hyperbole. He’s been very open about his intent to dismantle any component that could possibly tell him no or hold him accountable in any way, which would functionally make him a king. It’s far, far, far from an ideal choice, but it’s an obvious one.

      • @[email protected]
        link
        fedilink
        English
        168 months ago

        I was going to say “inb4 someone says that it’s Biden’s fault that congress did something” but I guess it’s too late for that.

      • SatansMaggotyCumFart
        link
        fedilink
        38 months ago

        Why doesn’t he just stick a lightbulb up the patient’s ass?

        Vote red because blue has blue hair.

  • Stern
    link
    fedilink
    338 months ago

    You can blame Newt Gingrich for that one, he installed in the R’s hyper partisanship and the idea that they can never let the D’s get a “win”. It carried them to a majority back in the 80’s, and much like voodoo economics, they haven’t changed the playbook since, since it still works.

  • @[email protected]
    link
    fedilink
    278 months ago

    To me it seems, a rich minority is gaming the system (political theatre, Fox news, CNN… --> public opinion), hoping to secure wealth and power against “the will of the people”, up to a point where the system will eventually break and be replaced by dictatorship.

    Ironically it is much more dangerous to be a billionaire in Russia or China than in the US or Europe.

    Maybe that should be our message: it seems easier to exploit us without checks and balances, but having none can be very dangerous for you and your family.

    However, the leader who will eventually emerge, the one using AI to check this comment, will be best for all of us, I’m sure!

  • @[email protected]
    link
    fedilink
    168 months ago

    Yes we all know that they fail at their jobs and fail to uphold anything that their office is supposed to stand for thereby failing the American people. Republicans are failures. That is an absolute fact.

  • Phoenixz
    link
    fedilink
    128 months ago

    I seriously hope they all get cancer themselves, just for the irony and to watch them claim they are still standing by their decision to die a gruesome death

  • @[email protected]
    link
    fedilink
    English
    128 months ago

    As someone who works in oncology data science, this is fucking infuriating. But also, politically, it’s 100% expected.