D-phenylalanine (enkephalinase inhibitor)

Interesting substance, its one of the few dextro (right-spinning optical isomer) amino acids that you can process or something.

I think its fascinating because its purportedly an endorphin reuptake enkephalinase inhibitor? or something so its potentially quasi-opioidergic. I’m not sold on the notion its legit but its definitely a provocative idea.

  • HubertManne
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    11 hour ago

    glycine. so if anyone is aware of cron there was a study which showd methionine restriction seemed to have a similar effect and a further study that glycine which helps eliminate glycine to do so as well as a supplement. Mouse studies though (not cron which has more data but the others are like one study each last I saw.)

  • @[email protected]
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    65 hours ago

    Glutamate is good to know about.

    It’s the oldest intercellular signaling chemical in evolutionary history. Sponges use glutamate to communicate between cells, so it predates nervous systems.

    It has tons of distinct meanings in the human body’s context, but mostly it means “fight or flight”. A state of excessive glutamate signaling, sometimes referred to as a “glutamate storm”, is associated with feelings of overwhelm and panic attacks.

    It can be blocked from binding by a chemical called L-theanine, which occurs naturally in tea and can be bought in pills at supplement stores. Studies have shown that people who take L-theanine supplements experienced reduced beta wave amplitude and increased alpha wave amplitude.

    In my own experience, L-theanine pills can basically nullify the “frozen” feeling I have with procrastinating on complex work, such as homework or software development, or even just complex decision-making.

    In other words, it’s the most effective anti-procrastination substance I’ve ever encountered. This is compared with:

    • anti-anxiety meds like xanax
    • blood pressure meds like propranolol
    • more coffee
    • adderall
    • ritalin
    • cocaine
    • alcohol
    • antidepressants
    • microdosed LSD
    • microdosed psilocybin
    • pseudoephidrine
    • maca

    … all taken at once. Not recommended

  • Philo
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    35 hours ago

    As a pirate, my favorite amino acid is arrrrr-genine 😁

  • ⚛️ Color 🎨
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    7 hours ago

    Tryptophan. It is a biochemical precursor for important neurotransmitters, vitamins and hormones such as melatonin, serotonin, and niacin. There happens to be very high concentrations of it in milk and eggs, both of which I love a lot. It can have sedating effects and make you feel chilled out!

  • @Worx
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    14 hours ago

    I’m gonna say D-phenylalanine because it’s the only one I know the name of ;)

    • @Semjaza
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      14 hours ago

      Also, when made of moly-mod it can stand up and looks like a giant robot.

  • @[email protected]
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    36 hours ago

    I’m going with the canned Mom ‘I love them all equally’ response because I don’t want any essential amino acid to feel scorned

  • Boozilla
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    36 hours ago

    Public schools and religious college failed me. I do not have a favorite amino acid.

  • Shadow
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    58 hours ago

    Lysine, because ingen tried to use it to control dinosaur populations.

  • @[email protected]
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    58 hours ago

    Probably plain L-phenylalanine, since it’s the precursor to phenethylamine, the body’s natural amphetamine.