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I’d deal with several seconds of consciousness, but the minutes to hours of agony when lethal injection fails to knock you out would be hell.
I asked my mother a long time ago why they don’t do executions under full anaesthesia, and she said it was to cause as much pain as possible which I fully believe.
The other thing I’ve recently seen pointed out is that they don’t have doctors administering it. Given the doctor ethos of “do no harm,” they can’t be involved and keep their license. So it’s just a bunch of underqualified people trying to figure out what to do.
Full transparency: I haven’t fact checked this myself, but it seemed feasible when it came up so it stuck with me.